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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Lou Moore | 2.081 | 2035 | |
| 2 | Manuel Schleusingen | 2.343 | 2035 | |
| 3 | Alfredo Soto | 2.359 | 2033 | |
| 4 | Ron Lawrence | 2.536 | 2049 | |
| 5 | Mike Cox | 2.544 | 2043 | |
| 6 | Cristo Pérez | 2.547 | 2035 | |
| 7 | Ron Powell | 2.619 | 2036 | |
| 8 | José Martínez | 2.649 | 2042 | |
| 9 | Rodrigo Morales | 2.721 | 2040 | |
| 10 | Meiji Ohayashi | 2.785 | 2044 | |
| 11 | Greg Curran | 2.786 | 2038 | |
| 12 | Jim Kaiser | 2.789 | 2018 | |
| 12 | Eddie Morgan | 2.789 | 2036 | |
| 12 | Zenon-Alejandro Paez | 2.789 | 2044 | |
| 15 | Jorge Cervantes | 2.818 | 2036 | |
| 16 | Ebby Calvin Laloosh | 2.826 | 2016 | |
| 17 | José Villarino | 2.837 | 2028 | |
| 18 | Ferry van Campen | 2.854 | 2044 | |
| 19 | Raúl De La Cruz# | 2.856 | 2055 | |
| 20 | Joe Mulder | 2.871 | 2037 | |
| 21 | José Sánchez# | 2.877 | 2052 | |
| 22 | José Rocha | 2.888 | 2041 | |
| 23 | Jeff Stanley | 2.914 | 2044 | |
| 24 | Dean Redmond# | 2.931 | 2047 | |
| 25 | Yasushi Yamaguchi | 2.935 | 2041 | |
| 26 | Sid Murdock | 2.951 | 2041 | |
| 27 | Mike Martin# | 2.986 | 2063 | |
| 28 | Chet Ward | 3.011 | 2038 | |
| 29 | Tangaloa Akeakamai# | 3.013 | 2063 | |
| 30 | Gil Crabtree | 3.019 | 2033 | |
| 31 | Luigi Paquet# | 3.050 | 2055 | |
| 32 | Randy Maire# | 3.054 | 2062 | |
| 33 | Leo Evans# | 3.064 | 2059 | |
| 34 | Kyoichi Kichikawa | 3.068 | 2038 | |
| 35 | Wilson Ortíz# | 3.086 | 2055 | |
| 36 | Tony Cantrell | 3.093 | 2017 | |
| 36 | José García | 3.093 | 2035 | |
| 38 | José Delgado | 3.094 | 2047 | |
| 39 | David Galloway | 3.097 | 2028 | |
| 40 | Alan Carpenter | 3.113 | 2045 | |
| 41 | Jermaine Larson | 3.115 | 2018 | |
| 42 | Héctor Maldonado | 3.118 | 2033 | |
| 43 | Gilberto Martínez | 3.135 | 2042 | |
| 44 | Wilson Deleón | 3.141 | 2019 | |
| 45 | Jeff Locke | 3.146 | 2045 | |
| 46 | Geoffrey McCluskey | 3.147 | 2042 | |
| 46 | David Galloway | 3.147 | 2027 | |
| 48 | Kevin Brooks | 3.153 | 2042 | |
| 48 | Robby Peterson | 3.153 | 2032 | |
| 50 | Jorge Cervantes | 3.161 | 2035 | |
| 51 | Jim Wilson | 3.164 | 2040 | |
| 52 | Sojuro Yoshikawa | 3.167 | 2032 | |
| 53 | Jorge Orozco | 3.197 | 2043 | |
| 53 | José Flores | 3.197 | 2040 | |
| 55 | Teruhide Nakamoto# | 3.201 | 2064 | |
| 56 | Randy Johnson | 3.226 | 2052 | |
| 57 | Vince Pope | 3.242 | 2060 | |
| 57 | Tony González | 3.242 | 2036 | |
| 59 | Cris Colón | 3.246 | 2039 | |
| 60 | Josh Reynolds# | 3.257 | 2063 | |
| 61 | Steve Miller | 3.261 | 2040 | |
| 62 | Tetsuhiko Kichida | 3.262 | 2022 | |
| 63 | Kevin Brooks | 3.264 | 2040 | |
| 64 | Jerry Sánchez | 3.266 | 2023 | |
| 65 | Ted Hunt | 3.271 | 2026 | |
| 66 | Nate Simpson | 3.276 | 2033 | |
| 67 | Cedric Miller | 3.288 | 2033 | |
| 68 | Raúl Pérez | 3.291 | 2046 | |
| 69 | Iván León | 3.293 | 2030 | |
| 70 | Jean-Marie Cochet | 3.304 | 2032 | |
| 71 | Víctor Cortéz# | 3.305 | 2058 | |
| 72 | Juan Reyes | 3.310 | 2048 | |
| 73 | Tom Phillips# | 3.311 | 2062 | |
| 74 | Juan Trevino | 3.319 | 2036 | |
| 75 | Jed Coatsworth | 3.321 | 2034 | |
| 76 | Norman Cornell* | 3.349 | 2035 | |
| 77 | Chad DeMarse# | 3.355 | 2056 | |
| 78 | Stan Williams | 3.360 | 2023 | |
| 78 | António Villasol | 3.360 | 2045 | |
| 80 | Ernesto Guzalán | 3.375 | 2042 | |
| 81 | António Mata | 3.403 | 2048 | |
| 82 | Juan López | 3.411 | 2042 | |
| 83 | Joaquín Rodríguez | 3.412 | 2038 | |
| 84 | Jim Burks | 3.416 | 2046 | |
| 84 | Brandon Auger# | 3.416 | 2064 | |
| 86 | Steve O'Keefe | 3.421 | 2043 | |
| 86 | Joe Mulder | 3.421 | 2038 | |
| 88 | Drew Duff | 3.429 | 2033 | |
| 89 | Mike Martin | 3.431 | 2014 | |
| 90 | Donnie Skinner | 3.436 | 2024 | |
| 91 | Rainer Windischgraetz# | 3.437 | 2058 | |
| 92 | Juan Cuevas | 3.442 | 2047 | |
| 93 | Chris Roberson | 3.446 | 2032 | |
| 94 | Jason Toth# | 3.448 | 2061 | |
| 95 | José Reyes | 3.451 | 2032 | |
| 96 | Jorge Morales# | 3.452 | 2058 | |
| 97 | Jorge Valarcel | 3.468 | 2039 | |
| 98 | Dave Harris | 3.479 | 2052 | |
| 98 | Tokutomi Inokuma | 3.479 | 2037 | |
| 100 | Chad Pelt# | 3.482 | 2064 |
